CREB3L1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP17243PU-N

CREB3L1 (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis: CREB3L1 Antibody (C-term) staining of Mouse stomach tissue lysates (35 ug/lane). CREB3L1 (arrow) was detected using the purified Pab.

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  CREB3L1 Antibody (C-term) staining of Formalin-Fixed, Paraffin-Embedded Human prostate carcinoma. This antibody was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.

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  Flow cytometric analysis of hela cells using CREB3L1 Antibody (C-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blot: 1/50-1/100.
  Flow cytometry: 1/10-1/50.
  Immunohistochemistry: 1/50-1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 488~517 amino acids from the C-terminal region of Human CREB3L1
• Specificity: This antibody detects CREB3L1 / OASIS at C-term.
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: cAMP responsive element binding protein 3-like 1
• Database Link:
  Entrez Gene 26427 MouseEntrez Gene 90993 Human
  UniProt ID Q96BA8
• Background: CREB3L1 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. It is specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). It may play a role in gliosis. In vitro, it binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.
• Synonyms: PSEC0238
• Note: Calculated Molecular weight: 57005 Da

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Huntington's disease, Melanogenesis, Prostate cancer