ANGPTL3 (N-term) Rabbit Polyclonal Antibody

CAT#: AP17105PU-N

ANGPTL3 (N-term) rabbit polyclonal antibody

Product Images

(LEFT) Western blot analysis of ANGPTL3 Antibody (N-term) ( #rified Pab. (RIGHT) Western blot analysis of ANGPTL3 Antibody (N-term) in mouse liver tissue lysates (35 ug/lane). ANGPTL3 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:1000.
  ELISA: 1:1,000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 82-114 amino acids from the N-terminal region of human ANGPTL3
• Specificity: This antibody detects Angiopoietin-5 at N-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: angiopoietin like 3
• Database Link:
  Entrez Gene 30924 MouseEntrez Gene 27329 Human
  UniProt ID Q9Y5C1
• Background: ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
• Synonyms: ANGPTL3, ANGPT5, Angiopoietin-like 3, ANG5, ANG-5
• Note: Molecular weight: 53637 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein