SAPK3 (MAPK12) Rabbit Polyclonal Antibody

CAT#: AP13903PU-N

SAPK3 (MAPK12) rabbit polyclonal antibody, Purified

Product Images

Formalin-fixed and paraffin-embedded human cancer tissue (hepatocarcinoma) reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: ELISA 1:1,000.
  Immunohistochemistry 1:50 - 1:100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human MAPK12.
• Specificity: This antibody detects p38 gamma (MAPK12) at center.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: mitogen-activated protein kinase 12
• Database Link:
  Entrez Gene 6300 Human
  UniProt ID P53778
• Background: Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. MAPK12 functions as a signal transducer during differentiation of myoblasts to myotubes.
• Synonyms: Mitogen-activated protein kinase 12, ERK5, Stress-activated protein kinase 3, p38 gamma, ERK6, SAPK3, MAP kinase p38 gamma
• Note: Molecular weight: 41940 Da