CAMK2G (C-term) Rabbit Polyclonal Antibody

CAT#: AP13886PU-N

CAMK2G (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of CAMK2G / CAMKG Antibody in K562 cell line lysates (35 ug/lane). CAMK2G (arrow) was detected using the purified Pab.

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  Western blot of CAMK2G / CAMKG Antibody to detect CAMK2 gamma in Mouse heart tissue lysate.

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  Formalin-fixed and paraffin-embedded human cancer tissue (hepatocarcinoma) reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blot: 1/1000.
  Immunohistochemistry: 1/50-1/100.
• Reactivities: Human, Mouse, Primate, Rat
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 309-338 amino acids from the C-terminal region of Human CAMK2G (CAMK2 gamma).
• Specificity: This antibody detects CAMK2G at C-term.
• Formulation: PBS
  State: Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 62609 Da
• Gene Name: calcium/calmodulin dependent protein kinase II gamma
• Database Link:
  Entrez Gene 12325 MouseEntrez Gene 171140 RatEntrez Gene 818 Human
  UniProt ID Q13555
• Background: CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.
• Synonyms: CaM-kinase II gamma chain, CaM kinase II subunit gamma, CaMK-II subunit gamma

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Calcium signaling pathway, ErbB signaling pathway, Glioma, GnRH signaling pathway, Long-term potentiation, Melanogenesis, Neurotrophin signaling pathway, Olfactory transduction, Oocyte meiosis, Wnt signaling pathway