AMHR2 (N-term) Rabbit Polyclonal Antibody

CAT#: AP13725PU-N

AMHR2 (N-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of AMHR2 (arrow) in mouse testis tissue lysates (35ug/lane) using AMHR2 antibody. (N-term).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  Western blot: 1/100-1/500.
  Enzyme immunoassay: 1/1000.

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region (between 20-50aa) of human AMHR2.
• Specificity: This antibody reacts to AMHR2.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: anti-Mullerian hormone receptor type 2
• Database Link:
  Entrez Gene 269 Human
  UniProt ID Q16671
• Background: The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.
• Synonyms: Anti-Muellerian hormone type-2 receptor, Anti-Muellerian hormone type II receptor, AMH type II receptor, MIS type II receptor, MISRII