Frataxin (FXN) (Center) Rabbit Polyclonal Antibody

CAT#: AP13488PU-N

Frataxin (FXN) (Center) rabbit polyclonal antibody, Purified

Product Images

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with FXN antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: ELISA: 1/1,000.
  Immunohistochemistry: 1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human FXN.
• Specificity: This antibody reacts to FXN.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: frataxin
• Database Link:
  Entrez Gene 2395 Human
  UniProt ID Q16595
• Background: FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.
• Synonyms: Frataxin mitochondrial, FRDA, Friedreich ataxia protein