alpha Internexin (INA) Rabbit Polyclonal Antibody

CAT#: AP13281PU-N

alpha Internexin (INA) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of INA (arrow) using rabbit polyclonal INA Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the INA gene (Lane 2)

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  Formalin-fixed and paraffin-embedded human brain tissue reacted with INA antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
  Immunohistochemistry: 1/10 - 1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human INA.
• Specificity: This antibody reacts to INA (alpha internexin).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: internexin neuronal intermediate filament protein alpha
• Database Link:
  Entrez Gene 9118 Human
  UniProt ID Q16352
• Background: INA is a class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.
• Synonyms: Alpha-Inx, INA, NEF5, NF66