Carbonic Anhydrase IX (CA9) (N-term) Rabbit Polyclonal Antibody
CAT#: AP13030PU-N
Carbonic Anhydrase IX (CA9) (N-term) rabbit polyclonal antibody, Purified
Other products for "CA9"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1/1,000. Western blotting: 1/100 - 1/500. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CA9. |
Specificity | This antibody reacts to CA9. |
Formulation | PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid purified Ig |
Concentration | lot specific |
Purification | Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | carbonic anhydrase 9 |
Database Link | |
Background | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. |
Synonyms | Carbonic anhydrase IX, Carbonate dehydratase IX, Membrane antigen MN, P54/58N, pMW1, CA9, CA IX, G250 |
Reference Data |
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