UBQLN2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP12093PU-N

UBQLN2 (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of anti-Dsk2 Pab (C-term) (Cat. #AP12093PU-N) to detect Dsk2 in HeLa cell lysate.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human Dsk2.
• Specificity: This antibody is specific to Ubiquilin-2 (UBQLN2/DSK2) (C-term).
• Formulation: State: Purified
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: ubiquilin 2
• Database Link:
  Entrez Gene 29978 Human
  UniProt ID Q9UHD9
• Background: Dsk2 increases the half-life of proteins destined to be degraded by the proteasome, and may modulate proteasome-mediated protein degradation. The Dsk2 protein binds UBE3A and BTRC, and interacts with the 19S proteasome subunit. In the cytoplasm, Dsk2 colocalizes with the proteasome; it is also associated with fibers in mitotic cells in the nucleus. Dsk2 is highly expressed in mitotic cells from metaphase to telophase, while expression in non-mitotic cells is very low.
• Synonyms: PLIC2, PLIC-2, N4BP4, Chap1, DSK2 homolog, HRIHFB2157
• Note: Predicted Molecular weight: 65765 Da