AP2 alpha (TFAP2A) (C-term) Rabbit Polyclonal Antibody

CAT#: AP11820PU-N

AP2 alpha (TFAP2A) (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of TFrified Pab (1:60 dilution).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA 1:1,000.
  Western blot 1:50 - 1:100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human TFAP2A.
• Specificity: This antibody detects TFAP2A at C-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: transcription factor AP-2 alpha
• Database Link:
  Entrez Gene 7020 Human
  UniProt ID P05549
• Background: TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.
• Synonyms: AP2TF, TFAP2, AP-2 transcription factor, Activator protein 2, AP2
• Note: Molecular weight: 47931 Da