KPNA4 (N-term) Rabbit Polyclonal Antibody

CAT#: AP11806PU-N

KPNA4 (N-term) rabbit polyclonal antibody, Purified

Product Images

The anti-Importin alpha-4 is used in Western blot to detect Importin alpha-4 in Hela (left), mouse brain (middle), and HepG2 (right)cell line/tissue lysates.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA 1:1,000.
  Western blot 1:250 - 1:500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Importin alpha-4.
• Specificity: This antibody detects Importin alpha-4 (KPNA4) at C-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: karyopherin subunit alpha 4
• Database Link:
  Entrez Gene 3840 Human
  UniProt ID O00629
• Background: The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
• Synonyms: QIP1, Karyopherin subunit alpha-4, Importin alpha Q1
• Note: Molecular weight: 57887 Da