alpha 1 Fetoprotein (AFP) (N-term) Rabbit Polyclonal Antibody
CAT#: AP11397PU-N
alpha 1 Fetoprotein (AFP) (N-term) rabbit polyclonal antibody, Aff - Purified
Other products for "AFP"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | ELISA 1:1,000. Immunohistochemistry 1:10 - 1:50. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human AFP. |
Specificity | This antibody detects AFP at N-term. |
Formulation | PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | alpha fetoprotein |
Database Link | |
Background | Alpha-fetoprotein (AFP) is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. This protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |
Synonyms | Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP |
Note | Molecular weight: 68678 Da |
Reference Data |
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