APOBEC3G (C-term) Rabbit Polyclonal Antibody

CAT#: AP11343PU-N

APOBEC3G (C-term) rabbit polyclonal antibody, Purified

Product Images

Western Blot analysis of anti-CEM15 Pab to detect CEM15 in A375 cell lysate.

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  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blot: 1/100-1/500.
  Immunohistochemistry: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This polyclonal antibody is generated from mice immunized with KLH conjugated synthetic peptides corresponding to C-terminal of human CEM15.
• Specificity: This antibody is specific to CEM15/APOBEC3G (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: apolipoprotein B mRNA editing enzyme catalytic subunit 3G
• Database Link:
  Entrez Gene 60489 Human
  UniProt ID Q9HC16
• Background: CEM15 is a member of the cytidine deaminase family. It is the product of one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. CEM15 has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.
• Synonyms: ARP9, CEM15, MDS019, APOBEC-3G, ARCD
• Note: Calculated MW: 46408 Da