VIP Rabbit Polyclonal Antibody

CAT#: AP09567SU-N

VIP rabbit polyclonal antibody, Serum

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Frozen and Paraffin Sections.
  Working Dilution: 1/2500-1/5000 using PAP, or 1/1500-1/3000 using FITC with overnight incubation at 2-8°C.
  Recommended Positive Control: Formalin-fixed paraffin sections of cat ileum.
• Reactivities: Feline, Fish, Human, Mammalian, Porcine, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Purified porcine VIP.
• Specificity: Antibody AM09102SU-N recognizes VIP (Vasoactive intestinal peptide).
  Absorption with 10-100 µg immunogen per ml diluted antiserum abolishes the staining, while PHI PHI, secretin, glucagon, GIP, and CCK do not.
• Formulation: State: Serum
  State: Lyophilized Undiluted Serum.
• Reconstitution Method: Dissolve the antiserum in 50-100 µl distilled water, and dilute further in 0.1 M PBS with 1% BSA and 0.09% Sodium Azide.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: vasoactive intestinal peptide
• Database Link:
  Entrez Gene 117064 RatEntrez Gene 7432 Human
  UniProt ID P01282
• Background: VIP is localized in nerve fibers of the central and peripheral nervous system, and is probably acting as a neurotransmitter. Smooth muscle relaxation, vasodilation and secretion from exocrine glands are some of the effects of VIP. The Verner-Morrison or Watery Diarrhea Hypokaliemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors. These VIP producing tumors are usually neuroblastomas of endocrine tumors in the pancreas.
• Synonyms: VIP, Vasoactive intestinal peptide

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane