PD1 (PDCD1) Rabbit Polyclonal Antibody

CAT#: AP07723PU-N

PD1 (PDCD1) rabbit polyclonal antibody, Purified

Product Images

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Skin.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Immunohistochemistry on FFPE-Sections: ~2.5 - 5 µg/ml (after heat induced antigen retrieval in pH 6.0 citrate buffer).
  Immunofluorescence.
  Western Blot. Expect a band at ~ 47 kD in size.
  THP-1 cell lysate can be used as positive control.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to 16 Amino Acid from near the carboxy terminus of Human PDCD1.
• Specificity: This antibody is specific to CD279/PDCD1
• Formulation: PBS containing 0.02% Sodium Azide as preservative.
  State: Purified
  State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for up to 3 months or at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: programmed cell death 1
• Database Link:
  Entrez Gene 5133 Human
  UniProt ID Q15116
• Background: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
• Synonyms: Protein PD-1, hPD-1, PDCD1