Caspase 2 (CASP2) Rabbit Polyclonal Antibody

CAT#: AP07690PU-N

Caspase 2 (CASP2) rabbit polyclonal antibody, Aff - Purified

Product Images

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Placenta.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Immunocytochemistry.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1 µg/ml.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic Peptide corresponding to 16 Amino Acid peptide from the amino-terminus of human Caspase-2.
• Formulation: Phosphate Buffered Saline PBS, containing 0.02% Sodium Azide as preservative.
  State: Aff - Purified
  State: Liquid purified IgG fraction.
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Dilute only prior to immediate use.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: caspase 2
• Database Link:
  Entrez Gene 835 Human
  UniProt ID P42575
• Background: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Although phylogenetically similar to this subfamily, Caspase-2 is thought to be involved in stress-induced apoptosis. Caspase-2 has two major isoforms; overexpression on the long form results in apoptosis while that of the short form suppresses cell death.
• Synonyms: CASP-2, CASP2, ICH1, ICH-1 protease, NEDD2