IRAKM (IRAK3) Rabbit Polyclonal Antibody

CAT#: AP07318PU-N

IRAKM (IRAK3) rabbit polyclonal antibody, Aff - Purified

Product Images

Tonsil: Formalin-Fixed Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 0.5 - 1 µg/ml.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide
• Specificity: This antibody reacts to a peptide corresponding to amino acids from the carboxy terminus of IRAK-M.
• Formulation: Phosphate buffered saline, containing 0.02% sodium azide
  State: Aff - Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: interleukin 1 receptor associated kinase 3
• Database Link:
  Entrez Gene 11213 Human
  UniProt ID Q9Y616
• Background: IRAK-M, an IRAK type protein kinase, is a signal transducer for the immune response Toll-like receptor and interleukin-1 (IL-1) receptor signaling cascades. IRAK-M is immediately downstream of the MyD88 adapter protein and immediately upstream of TRAF6. At least three mRNA transcripts have been reported - an approximately 8-kb doublet and a 2.5-kb transcript that matched isolated cDNA. IRAK-M (-/-) mice have increased inflammatory responses to bacterial infection.
• Synonyms: IRAK-3, IRAK-M