FOXD3 Rabbit Polyclonal Antibody

CAT#: AP06761PU-N

FOXD3 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of FoxD3 antibody in extracts from HUVEC cells.

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  Immunohistochemistry (IHC) analyzes of FoxD3 antibody in paraffin-embedded human heart tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 202-251 of Human FoxD3.
• Specificity: This antibody detects endogenous levels of FoxD3 protein.
  (region surrounding Arg233)
• Formulation: Phosphate buffered saline (PBS), pH~7.3
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 48.0 kDa
• Gene Name: forkhead box D3
• Database Link:
  Entrez Gene 27022 Human
  UniProt ID Q9UJU5
• Background: Embryonic stem cells require the forkhead transcriptional regulator FoxD3 for survival. Following gastrulation, FoxD3 generally gets downregulated, except in the neural crest. A variety of growth factors induce FoxD3 expression, including FGF8 and SNAIL, maintaining the effected cells in an undifferentiated state. Thus defects in FoxD3 induction may cause premature differentiation and/or migration-asociated birth defects.
• Synonyms: Forkhead box protein D3