CX3CR1 (N-term) Rabbit Polyclonal Antibody

CAT#: AP05786PU-N

CX3CR1 (N-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of human spleen lysate probed with Rabbit anti Human CX3CR1 Antibody either in the absence (Lane 1) or presence (Lane 2) of blocking peptide

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  Immunohistochemical staining of human heart tissue with anti Human CX3CR1 Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western Blot: 0.5-1.0 µg/ml. Detects a band of approximately 50kDa in Human spleen cell lysates.
  Immunohistochemistry on Paraffin Sections: 2.0 µg/ml.
  Requires Antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
  Positive Control: Human Heart Tissue.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A peptide corresponding to amino acids 2-21 of Human CX3CR1.
• Specificity: This antibody recognizes an epiptope within the N-terminal region (NT) of Human CX3CR1, a 40.4kDa seven trans-membrane protein.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: C-X3-C motif chemokine receptor 1
• Database Link:
  Entrez Gene 13051 MouseEntrez Gene 171056 RatEntrez Gene 1524 Human
  UniProt ID P49238
• Background: CX3CR1, known also as fractalkine receptor, is the receptor for CX3CL1 and acts as a co-receptor with CD4 for the HIV-1 envelope protein. It is expressed in a variety of human tissues and mediates leucocyte adhesion and migration.
• Synonyms: CX3C chemokine receptor 1, C-X3-C CKR-1,CMKBRL1, CMK-BRL-1

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction