SUPT16H Rabbit Polyclonal Antibody

CAT#: AP05153PU-N

SUPT16H rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 5 - 10 µg/ml.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein consisting of amino acids 1 - 329 of the human SPT16 protein conjugated to GST.
• Specificity: This antibody reacts to FACT complex subunit SPT16.
• Formulation: Phosphate buffered saline with 0.08% sodium azide
  State: Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: SPT16 homolog, facilitates chromatin remodeling subunit
• Database Link:
  Entrez Gene 11198 Human
  UniProt ID Q9Y5B9
• Background: SPT16 and SSRP1 are found in all eurkaryotic cells and exists as part of an essential heterodimer complex. Together, SPT16 and SSRP1 are a highly abundant nuclear complex that in mammals has been called FACT, or Facilitates Chromatin Transcription. FACT enhances the processivity of RNA polymerase II through nucleosomes. Evidence also points to a role for FACT in replication, possibly by enhancing DNA polymerase through nucleosomes as well.
• Synonyms: FACT complex subunit SPT16, FACTp140