STAT5A Rabbit Polyclonal Antibody

CAT#: AP02589PU-N

STAT5A rabbit polyclonal antibody, Aff - Purified

Product Images

Figure 2. Western blot analysis of extracts from HeLa cells using STAT5A antibody.

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  Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT5A antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western Blot: 1/500~1/1000.
  Immunohistochemistry: 1/50~1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human STAT5A around the phosphorylation site of Tyrosine 694 (D-G-YP-V-K).
• Specificity: This antibody detects endogenous levels of total STAT5A around Tyrosine 694.
• Formulation: PBS (without Mg2+ and Ca2+), pH 7.4 containing 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
  State: Aff - Purified
  State: Liquid purified IgG fraction.
• Concentration: lot specific
• Purification: Affinity Chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store the antibody (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: signal transducer and activator of transcription 5A
• Database Link:
  Entrez Gene 6776 Human
  UniProt ID P42229
• Background: STAT5a protein is a transcription factor activated by hormone and cytokines. Two highly related, but distinct Stat 5 genes (Stat 5a and Stat 5b) were identified in mouse. The amino acid sequences of Stat 5a and Stat 5b show 96% sequence similarity, and both proteins are co expressed in most tissues of both virgin and lactating mice. However, differential accumulation of Stat 5a and Stat 5b mRNA has been reported for both muscle and mammary tissue. Stat 5a is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.
• Synonyms: STAT-5, STAT-5A, Mammary gland factor, MGF
• Note: Predicted Molecular Weight: 91 kDa.