NMDAR1 (GRIN1) pSer896 Rabbit Polyclonal Antibody

CAT#: AP02396PU-N

NMDAR1 (GRIN1) pSer896 rabbit polyclonal antibody, Aff - Purified

Product Images

Figure 1. Western blot analysis of extract from MCF7 cells, untreated or treated with estradiol (100 nM, 20 min), using NMDAR1 (phospho-Ser896) antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Suitable for use in Western blot (1:500~1:1000).
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human NMDAR1 around the phosphorylation site of serine 896 (R-R-SP-S-K).
• Specificity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
  NMDAR1 (phospho-Ser896) antibody detects endogenous levels of NMDAR1 only when phosphorylated at serine 896.
• Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
  State: Aff - Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Immunoaffinity chromatography.
• Conjugation: Unconjugated
• Storage: Store the antibody (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Gene Name: glutamate ionotropic receptor NMDA type subunit 1
• Database Link:
  Entrez Gene 2902 Human
  UniProt ID Q05586
• Background: NMDA receptor subtypes of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. NMDAR1 plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission and is involved in the cell surface targeting of NMDA receptors.
• Synonyms: NMDAR1,GRIN1