Bone Sialoprotein (IBSP) (262-279) Rabbit Polyclonal Antibody

CAT#: AP02052SU-S

Bone Sialoprotein (IBSP) (262-279) rabbit polyclonal antibody, Serum

Specifications

Product Data

• Applications: ELISA, IF
• Recommended Dilution: ELISA (1/1000).
  Immunocytochemistry (1/100).
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic Human Bone Sialoprotein (aa 262-279)
• Specificity: This antibody detects Bone Sialoprotein (aa 262-279).
  Cross reactivity with Bone Sialoprotein.
  There were no cross reactivities obtained with Human Osteonectin, and Human Osteopontin (aa 25-40).
• Formulation: State: Serum
  State: Lyophilized Serum
• Reconstitution Method: Restore in aqua bidest to initial volume.
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Gene Name: integrin binding sialoprotein
• Database Link:
  Entrez Gene 3381 Human
  UniProt ID P21815
• Background: The protein encoded by the Bone Sialoprotein gene is a major structural protein of the bone matrix. It is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts, and it constitutes approximately 12% of the noncollagenous proteins in human bone. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
• Synonyms: Bone sialoprotein II, BSP II, IBSP, BNSP
• Note: LocusID 3381