Adenosine A1 Receptor (ADORA1) Rabbit Polyclonal Antibody

CAT#: AP01303PU-N

Adenosine A1 Receptor (ADORA1) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Adenosine A1-R antibody (Cat.-No.: AP01303PU-N) in extracts from MCF-7 cells.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: Immunofluorescence: 1/50-1/200.
  Western blot: 1/500-1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Adenosine A1-R protein (region surrounding Asp326).
• Formulation: Phosphate buffered saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 42 kDa
• Gene Name: adenosine A1 receptor
• Database Link:
  Entrez Gene 134 Human
  UniProt ID P30542
• Background: Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.
• Synonyms: ADORA1