Botulinum neurotoxin type E Rabbit Polyclonal Antibody

CAT#: AP00682PU-N

Botulinum neurotoxin type E rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: Dot Blot.
  ELISA.
  Western Blot.
• Reactivities: Clostridium botulinum
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Type E Neurotoxin and complexing Proteins
• Specificity: This antibody reacts to C. botulinum Type E Neurotoxin Complex, neurotoxin or protein isolates.
• Formulation: 1X PBS, pH 7.2 containing 20% glycerol
  State: Purified
  State: Liquid purified IgG
• Concentration: lot specific
• Purification: Protein G Sepharose chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  UniProt ID Q00496
• Background: Clostridium botulinum E Toxoid acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase. It has a non-toxic component which is necessary to maintain toxicity.
• Synonyms: Clostridium Botulinum Toxin E, BoNT/E, Bontoxilysin-E
• Note: Centrifuge before opening to ensure complete recovery of vial contents.