DGKA (C-term) Mouse Monoclonal Antibody [Clone ID: M6]

CAT#: AM33028PU-N

DGKA (C-term) mouse monoclonal antibody, clone M6, Purified

Product Images

Immunohistochemistry on paraffin section of human spleen. Antibody concentration 10ug/ml

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  Immunohistochemistry on paraffin section of human small intestine. Antibody concentration 10ug/ml

Specifications

Product Data

• Clone Name: M6
• Applications: IHC, IP, WB
• Recommended Dilution: Western blot.
  Immunoprecipitation.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Escherichia coli cell-expressed, affinity-purified Glutathione S-transferase fusion protein of a C-terminal portion (part of the catalytic domain) of Rat DGKu.
• Specificity: This Monoclonal M6 Antibody is directed against the C-terminal portion (part of the catalytic domain) of Rat DGK alpha.
• Formulation: PBS
  State: Purified
  State: Liquid purified fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: diacylglycerol kinase alpha
• Database Link:
  Entrez Gene 1606 Human
  UniProt ID P23743
• Background: Diacylglycerol kinase alpha is an enzyme that in humans is encoded by the DGKA gene. The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways.
  It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
  Tissue specificity: lymphocytes and oligodendroglial cells.
  Diacylglycerol kinases are involved in cell signaling, either as regulators of diacylglycerol levels or as intracellular signal-generating enzymes.
• Synonyms: Diacylglycerol kinase alpha, Diglyceride kinase alpha, DGKA, DAGK, DAGK1, DGK-alpha