LAMP1 Mouse Monoclonal Antibody [Clone ID: 5H6]

CAT#: AM32995PU-N

LAMP1 mouse monoclonal antibody, clone 5H6, Aff - Purified

Product Images

Western blot of HeLa lysate showing specific immunolabeling of the ~ 100k LAMP1 protein.

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  Immunofluorescence of HeLa cells showing strong punctate cytoplasmic labeling of LAMP1 corresponding to lysosomes and late endosomes in red.

Specifications

Product Data

• Clone Name: 5H6
• Applications: IF, WB
• Recommended Dilution: Western Blot: 1/5000.
  Immunofluorescence: 1/2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant full length Human LAMP1 expressed in and purified from E. Coli.
• Specificity: Specific for the ~100k LAMP1 protein.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified IgG fraction from Tissue Culture Supernatant
  Preservative: 10mM Sodium Azide
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: lysosomal associated membrane protein 1
• Database Link:
  Entrez Gene 3916 Human
  UniProt ID P11279
• Background: Lysosomal Associated Membrane Protein1 (LAMP1) is a protein that is localized primarily in lysosomes but may also be present on late endosomes and the plasma membrane. LAMP1 antibodies are therefore widely used as lysosome markers. It has recently been suggested that lysosomes are activated in microglia in the progression of multiple system atrophy (MSA) and thus play a key role in its pathology (Makioka et al., 2012).
• Synonyms: LAMP-1, LAMPA, LGP120