CD94 (KLRD1) Mouse Monoclonal Antibody [Clone ID: B-D49]

CAT#: AM32988FC-N

CD94 (KLRD1) mouse monoclonal antibody, clone B-D49, FITC, Purified

Product Images

typical staining pattern of lymphocytes with the B-D49 monoclonal antibody

Specifications

Product Data

• Clone Name: B-D49
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl to label 10⁶ cells or 100 µl of whole blood.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: IL-2 activated NK cells after tolerisation with activated PBL (CD56 negative).
• Specificity: This antibody recognizes cell surface CD94.
• Formulation: PBS
  Label: FITC
  State: Purified
  State: Liquid purified IgG fraction
  Stabilizer: 5% BSA
  Preservative: 0.09% Sodium Azide
• Purification: Ion Exchange Chromatography
• Conjugation: FITC
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Gene Name: killer cell lectin like receptor D1
• Database Link:
  Entrez Gene 3824 Human
  UniProt ID Q13241
• Background: Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
• Synonyms: KLRD1, KP43, NK cell receptor