IL2 Receptor alpha (IL2RA) Mouse Monoclonal Antibody [Clone ID: CD25-3G10]

CAT#: AM32321RP-N

IL2 Receptor alpha (IL2RA) mouse monoclonal antibody, clone CD25-3G10, PE

Specifications

Product Data

• Clone Name: CD25-3G10
• Recommended Dilution: Flow Cytometry: 5 μl is the maximum amount of reagent required for 1 x 10e6 cells.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity:

  The antibody reacts with the α chain of the Interleukin-2 Receptor (55 kD glycoprotein). CD25 is expressed on activated T-lymphocytes and B-lymphocytes.

• Formulation: Label: PE
  State: Liquid purified Ig fraction
  Preservative: 0,09% sodium azide
  Absorption emission: 488 nm / 575 nm
• Conjugation: PE
• Storage:

  Store the antibody undiluted at 2-8°C.
  <b>DO NOT FREEZE!</b>

• Stability: Shelf life: one year from despatch.

• Gene Name: interleukin 2 receptor subunit alpha
• Database Link:
  Entrez Gene 3559 Human
  UniProt ID P01589
• Background:

  CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemia's, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression.

• Synonyms: Interleukin-2 receptor alpha chain, IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, p55, TAC antigen