Ptprr Mouse Monoclonal Antibody [Clone ID: 6A6]
Other products for "Ptprr"
Specifications
Product Data | |
Clone Name | 6A6 |
Applications | IHC, IP, WB |
Recommended Dilution | Immunoprecipitation. Immunoblotting. Immunohistochemistry on Frozen Sections. |
Reactivities | Mouse |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Recombinant PTP-SL-GST (NCBI accession number BN000437, expression vector pGEX-2T), expressed in E.coli. |
Specificity | This antibody is directed to the common part of these proteins (PTPBR7, PTP-SL and PTPPBSγ). Specificity has been tested in Immunoprecipitation, Immunohistochemistry and Immunoblotting. Crossreacts with the striatum enriched phosphatase (STEP) when using antibody in Immunoblotting (Figure 1). Additional tests for cross reactivity have not yet been performed. |
Formulation | 10 mM Ammonium Bicarbonate buffer State: Purified State: Lyophilized purified Ig fraction |
Reconstitution Method | Dissolve in a 100 mM Tris-HCl pH8.0 buffer containing 0.05% Sodium Azide |
Concentration | lot specific |
Purification | Protein A Chromatography |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C. |
Stability | Shelf life: One year from despatch. |
Gene Name | protein tyrosine phosphatase, receptor type, R |
Database Link | |
Background | Protein tyrosine phosphatases (PTPs) are the enzymes that are instrumental in determining the spatial and temporal balance between the tyrosine phosphorylated and non-phosphorylated targets, and thus coordinately regulate these cellular responses to extracellular cues. The Ptprr gene gives rise to 4 different neuronal phosphatases which differ in length of their N-terminal part and subcellular localization. PTPBR7 (72 kDa) is receptor-like, PTP-SL (60 kDa) is membrane associated and PTPPBSγ (42 and 37 kDa) is a cytosolic phoaphatase. |
Synonyms | ECPTP, PTPRQ, R-PTP-R, PCPTP1, Ch-1PTPase, NC-PTPCOM1 |
Reference Data |
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