IL12A Mouse Monoclonal Antibody [Clone ID: B-T21]

CAT#: AM31263AF-N

IL12A mouse monoclonal antibody, clone B-T21, Azide Free

Specifications

Product Data

• Clone Name: B-T21
• Applications: FC, FN
• Recommended Dilution: Flow Cytometry (Intra-cytoplasmic).
  Functional Assay: Blocks IL-12 induced proliferation on PHA and IL-2 activated lymphocytes.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant Human IL-12.
• Specificity: This antibody recognizes both natural and recombinant Human IL-12 p35 + p70
• Formulation: Phosphate-buffered saline without Carrier and preservatives.
  This prodcut is sterile-filtered through 0.22 µm and treated to remove Endotoxins.
  State: Azide Free
  State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Ion Exchange Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: interleukin 12A
• Database Link:
  Entrez Gene 3592 Human
  UniProt ID P29459
• Background: Interleukin 12 (IL12) is an important cytokine produced by a variety of immune effector cells that leads to a type 1 helper T cell (Th1) response. IL12 also directs T cells to the skin via induction of cutaneous lymphocyte antigen (CLA) expression. Interleukin 12 is a heterodimeric cytokine (p70), composed of two covalently linked subunits, p35 and p40 and is secreted primarily by activated B cells.
• Synonyms: IL-12A, IL-12 subunit p35, NKSF1, CLMF p35

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Allograft rejection, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Type I diabetes mellitus