CD28 Mouse Monoclonal Antibody [Clone ID: B-T3]

CAT#: AM31233AF-N

CD28 mouse monoclonal antibody, clone B-T3, Azide Free

Product Images

A typical staining pattern with the B-T3 monoclonal antibody of lymphocytes

Specifications

Product Data

• Clone Name: B-T3
• Applications: FC, FN, IHC
• Recommended Dilution: Flow Cytometry.
  Immunohistochemistry.
  Functional Assay: Inhibits Mixed Lymphocyte Culture. Co-stimulates T cell proliferation.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: U266 cell line
• Specificity: This antibody recognises the B7/BB1 receptor (B7/BB1 R), a 44 kDa protein.
• Formulation: Phosphate-buffered saline.
  Sterile-filtered through 0.22 µm and treated to remove endotoxins.
  Carrier and preservative free.
  State: Azide Free
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Ion Exchange Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: CD28 molecule
• Database Link:
  Entrez Gene 940 Human
  UniProt ID P10747
• Background: CD28 contains 1 Ig-like V-type (immunoglobulin-like) domain. Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
• Synonyms: TP44

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, T cell receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis