CD56 Mouse Monoclonal Antibody [Clone ID: LT56]

CAT#: AM26771PU-N

CD56 mouse monoclonal antibody, clone LT56, Purified

Specifications

Product Data

• Clone Name: LT56
• Applications: ELISA, FC, WB
• Recommended Dilution: Flow cytometry.
  Western blot (non-reducing conditions).
  ELISA.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Cell line KG1a
• Specificity: This antibody recognizes CD56 (NCAM), a transmembrane glycoprotein expressed ubiquitously in the nervous system and found also on T cells and NK cells.
• Formulation: Phosphate buffered saline (PBS)
  State: Purified
  State: Liquid Ig fraction
  Preservative: 15 mM sodium azide, approx. pH 7.4
• Concentration: lot specific
• Purification: Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  
• Stability: Shelf life: one year from despatch.
• Gene Name: neural cell adhesion molecule 1
• Database Link:
  Entrez Gene 4684 Human
  UniProt ID P13591
• Background: CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.
• Synonyms: NCAM-1, N-CAM-1, NCAM

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Prion diseases