Complement C9 (C9) Mouse Monoclonal Antibody [Clone ID: X197]

CAT#: AM26242PU-N

Complement C9 (C9) mouse monoclonal antibody, clone X197, Purified

Specifications

Product Data

• Clone Name: X197
• Applications: ELISA, FN, IHC, WB
• Recommended Dilution: Immunohistochemistry on frozen and paraffin sections: The typical starting working dilution is 1:10.
  Flow cytometry: The typical starting working dilution is 1:10.
  Immunoassay.
  Western blot: The typical starting working dilution is 1:10.
  Functional assay: Inhibits C9 binding to C5b-8.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antibody detects C9.
• Formulation: PBS
  State: Purified
  State: Liquid 0.2 µm filtered Ig fraction
  Stabilizer: 0.1% bovine serum albumin
  Preservative: 0.02% sodium azide
• Concentration: lot specific
• Purification: Protein G
• Conjugation: Unconjugated
• Storage:

  Store at 2 - 8 °C.
  

• Stability: Shelf life: one year from despatch.

• Gene Name: complement component 9
• Database Link:
  Entrez Gene 735 Human
  UniProt ID P02748
• Background:
  Human C9 is a soluble glycoprotein of 61 kD. It is the last component in the assembly of the membrane attack complex (MAC). When the complement is activated on target membranes, multiple copies of C9 bind to the C5b-8 complex and assemble the barrel-shaped pore which causes cell lysis. The conformation of C9 changes from globular to a tubular form. The binding of C9 to C5b-8 plays a key role in the function of C9.
• Synonyms: Complement component C9, Complement 9