Laminin alpha 4 (LAMA4) Mouse Monoclonal Antibody [Clone ID: 6C3]

CAT#: AM26108PU-N

Laminin alpha 4 (LAMA4) mouse monoclonal antibody, clone 6C3, Purified

Product Images

Reactivity of laminin alpha4 chain specific monoclonal antibody 6C3 on human platelet lysate by Western blotting (reducing, R and nonreducing, NR conditions).

Specifications

Product Data

• Clone Name: 6C3
• Applications: ELISA, IP, WB
• Recommended Dilution: ELISA: 1:4000.
  Western blot (reduced conditions): 1:1 000 – 1:2 000.
  Immunoprecipitation: 1:20.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Immunoaffinity-purified Laminin 411 (laminin-8 (alpha4beta1gamma1) from Platelets
• Specificity: This antibody detects Laminin alpha 4.
• Formulation: PBS pH 7.4, with 0.09% sodium azide
  State: Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Ion-exchange chromatography
• Conjugation: Unconjugated
• Storage: Upon receipt, store (in aliquots) at -20 to -70 °C. Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Gene Name: laminin subunit alpha 4
• Database Link:
  Entrez Gene 3910 Human
  UniProt ID Q16363
• Background: Laminins are a family of large heterotrimeric proteins that promote cell adhesion and migration via integrins and other cell-surface receptors. They are major components of basement membranes of blood vessels and other tissue compartments, and are synthesized by numerous cell types. Through combination, laminin chains constitute 15 laminin isoforms. Laminin isoforms, particularly their alpha chain, are expressed in a celland tissue-specific manner, and are differentially recognized by integrins.
• Synonyms: LAMA4, Laminin subunit alpha-4

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer