CD71 (TFRC) Mouse Monoclonal Antibody [Clone ID: SOM4D10]

CAT#: AM26057PU-N

CD71 (TFRC) mouse monoclonal antibody, clone SOM4D10, Aff - Purified

Product Images

Immunohistochemistry on frozen sections: Staining of human tonsil with AM26057PU-N

Specifications

Product Data

• Clone Name: SOM4D10
• Applications: FC, IHC
• Recommended Dilution: Immunohistochemistry on frozen sections: 1-3 μg/ml (1:130 - 1:400).
  Has been described to work in FACS.
  Suggested positive control: Human tonsil.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Specificity: This antibody recognizes the human CD71 antigen, the transferrin receptor.
• Formulation: Stock solution contains 0.4mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA), and 0.09% sodium azide as a preservative
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: Reconstitute by adding 0.5 ml distilled water.
• Purification: Affinity chromatography
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: transferrin receptor
• Database Link:
  Entrez Gene 7037 Human
  UniProt ID P02786
• Background: CD71 is a proliferation-associated homodimeric membrane glycoprotein consisting of two disulfide-bonded 95kD chains. CD71 is a type II membrane protein with short aminoterminal cytoplasmic domain which mediates internalization and recycling, a single transmembrane region, and a large extracellular transferrin-binding domain. CD71 contains N-linked and O-linked glycans, as well as palmitic acid covalently attached to cysteine residues close to the cytoplasmic face of the membrane.
• Synonyms: TfR1, p90, Transferrin receptor protein 1
• Note: Antigen distribution:
  Isolated cells: The antibody stains > 90% of activated human peripheral blood lymphocytes in flow cytometry.
  Tissue sections: Germinal center; basal layer of epidermis; tissue macrophages; testis.

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protease, Secreted Protein, Transmembrane
• Protein Pathways: Endocytosis, Hematopoietic cell lineage