CDK7 Mouse Monoclonal Antibody [Clone ID: IMD-26]

CAT#: AM20606PU-N

CDK7 mouse monoclonal antibody, clone IMD-26, Purified

Specifications

Product Data

• Clone Name: IMD-26
• Applications: IF, IHC, WB
• Recommended Dilution: Western Blot: 0.25 μg/ml.
  Immunohistochemistry on frozen sections: 0.5 μg/ml.
  Immunocytochemistry.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant human Cdk7 protein.
• Specificity: This antibody reacts to CDK7.
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
  State: Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS.
• Concentration: 0,1 mg/ml (after reconstitution with PBS)
• Purification: Affinity chromatography
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: cyclin-dependent kinase 7
• Database Link:
  Entrez Gene 1022 Human
  UniProt ID P50613
• Background: CDK-activating kinases (CAKs) are multisubunit proteins that phosphorylate and thus activate certain cyclin-dependent protein kinases in the regulation of cell cycle progression. Cyclin dependent kinase7( CDK7) gene is mapped to chromosome 2p15-cen. CDK7 functions in both cyclin binding and T-loop phosphorylation and that these 2 steps of CDK1 activation are mutually dependent.
• Synonyms: CAK1, P39 Mo15, STK1, CDK-activating kinase

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Stem cell - Pluripotency, Transcription Factors
• Protein Pathways: Cell cycle, Nucleotide excision repair