CDK6 Mouse Monoclonal Antibody [Clone ID: IML-6]

CAT#: AM20605PU-N

CDK6 mouse monoclonal antibody, clone IML-6, Purified

Specifications

Product Data

• Clone Name: IML-6
• Applications: IF, WB
• Recommended Dilution: Western Blot: 0.1 - 0.5 μg/ml.
  Immunocytochemistry: 1 ug/ml.
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human Cdk6 protein.
• Specificity: This antibody reacts to CDK6.
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
  State: Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS
• Concentration: 0,1 mg/ml (after reconstitution with PBS)
• Purification: Purified by the goat anti-mouse IgG affinity chromatography.
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: cyclin-dependent kinase 6
• Database Link:
  Entrez Gene 12571 MouseEntrez Gene 114483 RatEntrez Gene 1021 Human
  UniProt ID Q00534
• Background: The cyclin-dependent protein kinases (CDKs) regulate major cell cycle transitions in eukaryotic cells.Cyclin-dependent kinase-6 (CDK6) is the earliest inducible member of the CDK family in human T lymphocytes, involved in growth factor stimulation and cell cycle progression. germline mutations in CDK6 do not make a significant contribution to melanoma predisposition. CDK6 gene is mapped at 7q21-q22.
• Synonyms: PLSTIRE

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Cell cycle, Chronic myeloid leukemia, Glioma, Melanoma, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Pathways in cancer, Small cell lung cancer