Transglutaminase-2 Mouse Monoclonal Antibody [Clone ID: 7D2]

CAT#: AM10223PU-N

Transglutaminase-2 mouse monoclonal antibody, clone 7D2, Purified

Product Images

Western Blot (10% gel) withTransglutaminase-2 antibody Cat.-NoAM10223PU-N

Specifications

Product Data

• Clone Name: 7D2
• Applications: ELISA, IHC, WB
• Recommended Dilution:

  ELISA.
  Western Blot: 1/200-1/1000.
  Immunohistochemistry: 1/100-1/500.

• Reactivities: Guinea Pig, Human
• Host: Mouse
• Isotype: IgG3
• Clonality: Monoclonal
• Immunogen: Purifed Transglutaminase 2 from Guinea Pig liver
• Specificity: Reacts with Guinea Pig TGM2 protein. React in liver and blood cells (erythrocytes).
  Also reacts with recombinant Human tissue Transglutaminase (rh-TGase-2)
• Formulation: 0.1M Tris, 0.1M Glycine and 2% Sucrose
  State: Purified
  State: Lyophilized purified antibody
  Preservative: None
• Reconstitution Method: Restore in distilled water.
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  UniProt ID P08587
• Background: Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.