CD56 (NCAM1) Mouse Monoclonal Antibody [Clone ID: 123C3.D5]

CAT#: AM10068SU-N

CD56 (NCAM1) mouse monoclonal antibody, clone 123C3.D5, Supernatant

Product Images

Formalin-Fixed, Paraffin-Embedded Human neuroendocrine carcinoma stained with CD56 antibody Cat.-No. AM10068SU-N using peroxidase conjugate and DAB chromogen. Note cell membrane staining of tumor cells.

Specifications

Product Data

• Clone Name: 123C3.D5
• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/100
  Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended.
  Use Polymer anti Mouse/Rabbit IgG as a detection system.
  Positive Control: Neuroblastoma, neuroendocrine carcinoma.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Membrane preparation of a small cell lung carcinoma.
• Specificity: Recognizes CD56/NCAM-1.
  Cellular Localization: Cell membrane.
• Formulation: State: Supernatant
  State: Liquid Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: neural cell adhesion molecule 1
• Database Link:
  Entrez Gene 9332 HumanEntrez Gene 4684 Human
  UniProt ID P13591
• Background: Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule which is glycosylated or sialylated to produce the mature species. NCAM (CD56) is reported to express on most neuroectodermal derived cell lines, tissues, and neoplasms such as retinoblastoma, medullblastoma, astrocytoma, and neuroblastoma. It is also expressed on some mesodermally derived tumors such as rhabdomyosarcoma and also on natural killer cells.
• Synonyms: NCAM-1, N-CAM-1, NCAM

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane