CCK4 (PTK7) Mouse Monoclonal Antibody [Clone ID: 4F9]

CAT#: AM06487SU-N

CCK4 (PTK7) mouse monoclonal antibody, clone 4F9, Ascites

Product Images

Western blot analysis using PTK7 mouse mAb against Hela (1), A431 (2), HCT116 (3), Caco2 (4), HepG2 (5) and MCF-7 (6) cell lysate.

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  Immunohistochemical analysis of paraffin-embedded lung cancer tissues using PTK7 mouse mAb with DAB staining.

Specifications

Product Data

• Clone Name: 4F9
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/10000.
  Western Blot: 1/500 - 1/2000.
  Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Human PTK7 expressed in E. Coli.
• Specificity: Recognizes PTK7
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 118 kDa
• Gene Name: protein tyrosine kinase 7 (inactive)
• Database Link:
  Entrez Gene 5754 Human
  UniProt ID Q13308
• Background: Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.Tissue specificity: Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.
• Synonyms: Tyrosine-protein kinase-like 7, Colon carcinoma kinase 4, CCK-4