STAT6 Mouse Monoclonal Antibody [Clone ID: 7D3]
Other products for "STAT6"
Specifications
Product Data | |
Clone Name | 7D3 |
Applications | ELISA, IF, WB |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. |
Reactivities | Human, Monkey, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human STAT6 expressed in E. Coli. |
Specificity | This antibody reacts to STAT6. |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 94 kDa |
Gene Name | signal transducer and activator of transcription 6 |
Database Link | |
Background | STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. |
Synonyms | IL-4 Stat |
Reference Data |
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in shipping.