MPS1 (RPS27) Mouse Monoclonal Antibody [Clone ID: 7E3]

CAT#: AM06343SU-N

MPS1 (RPS27) mouse monoclonal antibody, clone 7E3, Ascites

Product Images

Confocal immunofluorescence analysis of Hela cells (A), BCBL-1 cells (B) and L1210 cells (C) using MPS1 antibody Cat.-No AM06343SU-N (green). Blue: DRAQ5 fluorescent DNA dye.

Specifications

Product Data

• Clone Name: 7E3
• Applications: ELISA, IF
• Recommended Dilution: ELISA: 1/10000.
  Immunofluorescence: 1/200 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of MPS1 expressed in E. Coli.
• Specificity: Recognizes MPS1, also known as RPS27.
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 95 kDa
• Gene Name: ribosomal protein S27
• Database Link:
  Entrez Gene 6232 Human
  UniProt ID P42677
• Background: MPS1, also known as RPS27. It is a ribosomal protein. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. MPS1 is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
• Synonyms: MPS1, Metallopan-stimulin 1, MPS-1, 40S ribosomal protein S27