FAK (PTK2) Mouse Monoclonal Antibody [Clone ID: 4A9D6]

CAT#: AM06120SU-N

FAK (PTK2) mouse monoclonal antibody, clone 4A9D6, Ascites

Product Images

Western blot analysis using FAK antibody Cat.-No AM06120SU-N against truncated FAK recombinant protein.

Specifications

Product Data

• Clone Name: 4A9D6
• Applications: ELISA, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.
  ELISA: 1/10000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of FAK expressed in E. Coli.
• Specificity: Recognizes FAK
• Formulation: State: Ascites
  State: Ascitic fluid
  Preservative: 0.03% Sodium Azide
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: protein tyrosine kinase 2
• Database Link:
  Entrez Gene 5747 Human
  UniProt ID Q05397
• Background: Focal adhesion kinase(FAK), with 1074 -amino acid protein(about 118 kDa), is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. FAK is concentrated at the basal edge of only basal keratinocytes that are actively migrating and rapidly proliferating in repairing burn wounds, and is activated and localized to the focal adhesions of spreading keratinocytes in culture. Thus, it has been postulated that FAK may have an important in vivo role in the re-epithelialization of human wounds. FAK protein tyrosine kinase activity has also been shown to increase in cells stimulated to grow by use of mitogenic neuropeptides or neurotransmitters acting through G protein-coupled receptors.
• Synonyms: FAK, Focal adhesion kinase 1, FADK1, pp125FAK, Protein-tyrosine kinase 2