BNP (NPPB) (NT-proBNP 13-27) Mouse Monoclonal Antibody [Clone ID: 18H5]

CAT#: AM05620PU-N

BNP (NPPB) (NT-proBNP 13-27) mouse monoclonal antibody, clone 18H5, Purified

Specifications

Product Data

• Clone Name: 18H5
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blotting: Detects a band of approximately 9kDa when using recombinant NT-proBNP.
  Immunoassay.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Amino acids 13-27 of NT-proBNP
• Specificity: This antibody detects the amino-terminal fragment of pro-brain natriuretic peptide (amino acids 13-20), also known as NT-proBNP, a cleavage product during the proteolytic activation of BNP.
• Formulation: Phosphate buffered saline pH 7.4 containing 0.09% Sodium Azide (NaN3)
  State: Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: natriuretic peptide B
• Database Link:
  Entrez Gene 4879 Human
  UniProt ID P16860
• Background: NT-proBNP is a secreted protein which is a member of the natriuretic peptide family, which is predominantly secreted from the cardiac ventricles in response to volume and pressure overload.
  NT-proBNP is more stable than BNP in serum, and has become a useful biomarker of heart failure.
• Synonyms: NPPB, Brain natriuretic peptide, BNP, proBNP