CD321 / JAM1 Rat Monoclonal Antibody [Clone ID: BV12]

CAT#: AM05553PU-S

CD321 / JAM1 rat monoclonal antibody, clone BV12, Purified

Specifications

Product Data

• Clone Name: BV12
• Applications: ELISA, FC, IF
• Recommended Dilution: Flow cytometry: The typical starting working dilution is 1:50.
  Immunoassays.
  Immunoflourescence.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Specificity: This antibody recognizes junctional adhesion molecule-A (JAM-A), also known as JAM-1 and the mouse platelet F11-Receptor (F11R).
• Formulation: PBS
  State: Purified
  State: Liquid 0.2 µm filtered Ig fraction
  Stabilizer: 0.1% bovine serum albumin
  Preservative: 0.02% sodium azide
• Concentration: lot specific
• Purification: Protein G
• Conjugation: Unconjugated
• Storage:

  Store at 2 - 8 °C.
  

• Stability: Shelf life: one year from despatch.

• Gene Name: F11 receptor
• Database Link:
  Entrez Gene 16456 Mouse
  UniProt ID O88792
• Background: JAM-A is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular junctions of endothelial cells and epithelial cells. JAM-A belongs together with JAM-B (VE-JAM or JAM-3) and JAM-C (JAM-2) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. In human JAM-A plays a role in platelet aggregation, secretion, adhesion and spreading.
• Synonyms: JAM-A, Platelet F11 receptor, F11R, JCAM, PAM1