Cardiac Troponin I (TNNI3) (65-74) Mouse Monoclonal Antibody [Clone ID: B158M]

CAT#: AM05142PU-N

Cardiac Troponin I (TNNI3) (65-74) mouse monoclonal antibody, clone B158M, Purified

Specifications

Product Data

• Clone Name: B158M
• Applications: ELISA, IHC, IP, WB
• Recommended Dilution: Immunoassay
  Immunoprecipitation.
  Immunohistochemistry.
  Immunoaffinity purification.
  Western blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Free human cTnI and native human cTn complex.
• Specificity: This antibody reacts with free cardiac troponin I (cTnI). Does not react with cTnI forming complexes with other troponin components. Not affected by phosphorylation. Recognizes an epitope between amino acid residues 65 and 74 of cTnI. No crossreactivity with skeletal muscle cTnI.
• Formulation: PBS, pH 7.4 containing 0,09% sodium azide
  State: Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Protein A chromatography >90% pure (SDS-PAGE).
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Gene Name: troponin I3, cardiac type
• Database Link:
  Entrez Gene 7137 Human
  UniProt ID P19429
• Background: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.
• Synonyms: TNNI3, TNNC1