Grm5 (824-1203, Cytopl. Dom.) Mouse Monoclonal Antibody [Clone ID: N75/33]

CAT#: 75-116

Grm5 (824-1203, Cytopl. Dom.) mouse monoclonal antibody, clone N75/33

Product Images

Immunoblots on membranes prepared from whole mouse (MBM) and rat (RBM) brain, and from human cerebellum [HBM(Cb)], cerebral cortex [HBM(Cx)], and hippocampus [HBM(H)].

• 

  Adult rat brain membrane immunoblot.

• 

  Electron micrograph shows N75/33 immunolabelling in the stratum radiatum of mouse hippocampal CA1 using a pre-embedding immunogold method. Immunogold particles were observed at postsynaptic sites (arrows) along the extrasynaptic plasma membrane of dendritic spines (s) and shafts (Den) of pyramidal cells establishing synaptic contacts with excitatory.

• 

  Adult rat hippocampus immunohistochemistry.

Specifications

Product Data

• Clone Name: N75/33
• Applications: IHC, IP, WB
• Recommended Dilution: Immunoblot (IB)
  Immunohistochemistry (IHC)
  Immunoprecipitation (IP)
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b (also known as metabotropic glutamate receptor 5, accession number P31424).
  Mouse: 96% identity (368/388 amino acids identical).
  Human: 87% identity (339/388 amino acids identical).
  <35% identity with mGluR1.
• Formulation: State: Purified
• Conjugation: Unconjugated
• Gene Name: glutamate metabotropic receptor 5
• Database Link:
  Entrez Gene 24418 Rat
  UniProt ID P31424
• Synonyms: Metabotropic glutamate receptor 5, GPRC1E, MGLUR5, GRM5, Metabotropic glutamate receptor 1, MGLUR1, GRM1, GPRC1A
• Note: USERS will cite the UC Davis/NIH NeuroMab Facility in any publication(s) describing the research utilizing the MATERIALS. The suggested acknowledgment statement is as follows:
  "The monoclonal antibody _ was developed by and/or obtained from the UC Davis/NIH NeuroMab Facility, supported by NIH grant U24NS050606 and maintained by the Department of Neurobiology, Physiology and Behavior, College of Biological Sciences, University of California, Davis, CA 95616."
  Also, please include the complete clone number (e.g., N52A/42) and the Antibody Registry identification number (e.g., RRID:AB_2120479) to avoid ambiguity.
  View Research License Agreement