ARNTL2 (NM_001248003) Human Untagged Clone

CAT#: SC332126

ARNTL2 (untagged) - Homo sapiens aryl hydrocarbon receptor nuclear translocator-like 2 (ARNTL2), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARNTL2
• Synonyms: bHLHe6; BMAL2; CLIF; MOP9; PASD9
• Vector: pCMV6-Entry
• Sequence Data:
  Fully Sequenced ORF

  >SC332126 representing NM_001248003.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  ATGGCGGCGGAAGAGGAGGCTGCGGCGGGAGGTGAGGTTGCCGGTGGCGAGGCGACGGCCCCAGGTAAA
  GTGTTGAGAGAGGAGAACCAGTGCATTGCTCCTGTGGTTTCCAGCCGCGTGAGTCCAGGGACAAGACCA
  ACAGCTATGGGGTCTTTCAGCTCACACATGACAGAGTTTCCACGAAAACGCAAAGGAAGTGATTCAGAC
  CCATCCCAAGAAGCTCATAGCCAAACTGAAAAGCGGAGGAGAGATAAAATGAATAACCTGATTGAAGAA
  CTGTCTGCAATGATCCCTCAGTGCAACCCCATGGCGCGTAAACTGGACAAACTTACAGTTTTAAGAATG
  GCTGTTCAACACTTGAGATCTTTAAAAGGCTTGACAAATTCTTATGTGGGAAGTAATTATAGACCATCA
  TTTCTTCAGGATAATGAGCTCAGACATTTAATCCTTAAGACTGCAGAAGGCTTCTTATTTGTGGTTGGA
  TGTGAAAGAGGAAAAATTCTCTTCGTTTCTAAGTCAGTCTCCAAAATACTTAATTATGATCAGGCTAGT
  TTGACTGGACAAAGCTTATTTGACTTCTTACATCCAAAAGATGTTGCCAAAGTAAAGGAACAACTTTCT
  TCTTTTGATATTTCACCAAGAGAAAAGCTAATAGATGCCAAAACTGGTTTGCAAGTTCACAGTAATCTC
  CACGCTGGAAGGACACGTGTGTATTCTGGCTCAAGACGATCTTTTTTCTGTCGGATAAAGAGTTGTAAA
  ATCTCTGTCAAAGAAGAGCATGGATGCTTACCCAACTCAAAGAAGAAAGAGCACAGAAAATTCTATACT
  ATCCATTGCACTGGTTACTTGAGAAGCTGGCCTCCAAATATTGTTGGAATGGAAGAAGAAAGGAACAGT
  AAGAAAGACAACAGTAATTTTACCTGCCTTGTGGCCATTGGAAGATTACAGCCATATATTGTTCCACAG
  AACAGTGGAGAGATTAATGTGAAACCAACTGAATTTATAACCCGGTTTGCAGTGAATGGAAAATTTGTC
  TATGTAGATCAAAGGGCAACAGCGATTTTAGGATATCTGCCTCAGGAACTTTTGGGAACTTCTTGTTAT
  GAATATTTTCATCAAGATGACCACAATAATTTGACTGACAAGCACAAAGCAGTTCTACAGAGTAAGGAG
  AAAATACTTACAGATTCCTACAAATTCAGAGCAAAAGATGGCTCTTTTGTAACTTTAAAAAGCCAATGG
  TTTAGTTTCACAAATCCTTGGACAAAAGAACTGGAATATATTGTATCTGTCAACACTTTAGTTTTGGGA
  CATAGTGAGCCTGGAGAAGCATCATTTTTACCTTGTAGCTCTCAATCATCAGAAGAATCCTCTAGACAG
  TCCTGTATGAGTGTACCTGGAATGTCTACTGGAACAGTACTTGGTGCTGGTAGTATTGGAACAGATATT
  GCAAATGAAATTCTGGATTTACAGAGGTTACAGTCTTCTTCATACCTTGATGATTCGAGTCCAACAGGT
  TTAATGAAAGATACTCATACTGTAAACTGCAGGAGTATGTCAAATAAGGAGTTGTTTCCACCAAGTCCT
  TCTGAAATGGGGGAGCTAGAGGCTACCAGGCAAAACCAGAGTACTGTTGCTGTCCACAGCCATGAGCCA
  CTCCTCAGTGATGGTGCACAGTTGGATTTCGATGCCCTATGTGACAATGATGACACAGCCATGGCTGCA
  TTTATGAATTACTTAGAAGCAGAGGGGGGCCTGGGAGACCCTGGGGACTTCAGTGACATCCAGTGGACC
  CTCTAG
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001248003
• Insert Size: 1800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001248003.1
• RefSeq Size: 7300 bp
• RefSeq ORF: 1800 bp
• Locus ID: 56938
• UniProt ID: Q8WYA1
• Cytogenetics: 12p11.23
• Protein Families: Druggable Genome, Transcription Factors
• MW: 66.5 kDa
• Gene Summary: This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
  Transcript Variant: This variant (3) uses an alternate in-frame donor splice site, and lacks two consecutive in-frame coding exons compared to variant 1. This results in a shorter isoform (3) compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.