WDR23 (DCAF11) (NM_025230) Human Untagged Clone

CAT#: SC321946

DCAF11 (untagged)-Human DDB1 and CUL4 associated factor 11 (DCAF11), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WDR23
• Synonyms: GL014; PRO2389; WDR23
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_025230.3 GAGCGAAGCGCGTGACGGAGGAGCGGTTGGCCAACGCAGTGGCGGCAGTCGGTGTAAACA
  AGGCCTCGCGCCGCTGCGGGTCCTGCGACCGCTCCTGGCTGGAGGTGACAGGAGGAGCCC
  CCGCACAGGACCTAAGAATGCTGTGACCAGAAGATGGGATCGCGGAACAGCAGCAGTGCA
  GGATCCGGGTCCGGAGACCCCTCCGAGGGCTTGCCCCGAAGAGGGGCTGGCCTGCGTCGG
  AGTGAGGAAGAGGAAGAAGAGGATGAAGATGTGGATCTGGCCCAGGTACTGGCCTATCTC
  CTCCGCAGAGGCCAAGTGAGGTTGGTGCAGGGAGGAGGTGCAGCAAATTTACAATTCATT
  CAGGCCCTCTTGGACTCAGAGGAAGAGAATGACAGAGCTTGGGATGGTCGTCTTGGGGAT
  CGATACAACCCACCTGTGGATGCTACCCCTGACACCCGGGAGCTGGAATTCAATGAGATC
  AAGACACAAGTGGAACTGGCCACAGGGCAGCTGGGGCTTAGGCGGGCCGCCCAGAAGCAC
  AGCTTTCCTCGAATGTTGCACCAGAGAGAACGGGGCCTCTGCCATCGGGGAAGCTTCTCC
  CTTGGAGAACAGTCTCGAGTGATATCTCACTTCTTGCCCAATGATCTGGGCTTCACTGAT
  AGCTACTCTCAGAAGGCTTTCTGTGGCATCTACAGCAAAGATGGTCAAATATTCATGTCT
  GCTTGCCAAGACCAGACAATCCGACTCTATGACTGCCGATATGGCCGTTTCCATAAATTC
  AAGAGCATCAAGGCCCGCGATGTAGGCTGGAGCGTCTTGGATGTGGCCTTCACCCCTGAT
  GGGAACCACTTCCTCTACTCTAGCTGGTCTGATTACATTCATATCTGCAATATCTATGGT
  GAGGGAGATACACACACTGCCCTGGATCTCAGGCCAGATGAGCGTCGCTTTGCTGTCTTC
  TCCATTGCTGTCTCCTCAGATGGACGAGAAGTACTAGGAGGGGCCAATGATGGCTGCCTG
  TATGTCTTTGACCGAGAACAGAACCGGCGCACCCTTCAGATTGAGTCCCATGAGGATGAT
  GTGAATGCAGTGGCCTTTGCTGATATAAGCTCCCAAATCCTGTTCTCTGGGGGAGATGAT
  GCCATCTGCAAAGTGTGGGATCGACGCACCATGCGGGAGGATGACCCCAAGCCTGTGGGT
  GCACTGGCTGGACACCAGGATGGCATCACCTTCATTGACAGCAAGGGTGATGCCCGGTAT
  CTGATCTCCAACTCTAAAGACCAGACCATCAAACTCTGGGATATCCGACGCTTTTCCAGC
  CGGGAAGGCATGGAAGCTTCACGCCAGGCTGCCACACAGCAAAACTGGGACTATCGGTGG
  CAGCAAGTGCCCAAAAAAGCCTGGCGGAAGCTGAAGCTCCCAGGGGACAGCTCCTTGATG
  ACCTACCGGGGCCACGGAGTGCTGCACACCCTCATCCGCTGCCGGTTCTCCCCCATTCAT
  AGCACTGGCCAGCAGTTCATCTACAGTGGCTGCTCCACTGGCAAAGTGGTTGTGTACGAC
  CTTCTAAGTGGCCACATTGTGAAGAAGCTGACCAACCACAAGGCCTGTGTGCGTGACGTC
  AGTTGGCACCCCTTTGAAGAGAAGATTGTCAGCAGTTCGTGGGACGGGAACCTGCGTCTG
  TGGCAGTACCGCCAGGCTGAGTACTTCCAGGATGACATGCCAGAATCTGAGGAATGTGCC
  AGCGCCCCTGCCCCAGTGCCCCAATCCTCTACACCCTTTTCCTCACCCCAGTAGATCCAA
  CCTCCAGCCCCATATAGGGTGAACCTCTTGATAAGCTCTCTGCCTCCTCCTCCCTTTCTC
  CCTTGTGGGGAATGTTTGGAGGAATCACTGGCATTTGATGGGGAATAACATAAGCCTGGG
  CTCTGAGCCTCAGCTGAGCCCTGGAAGATTCTCCCCATGGGGCAGAGTGGTCTCCTTACG
  TGCTCACACCCAGTCAGCTTGGGTCCCTATCTCTGGCCAGAGTTTGGCAGGACTGCCATT
  ATCTGGGGTGTGGCCTCTGCCAGCAAGAGAAGTGTCCTGGGTGTTTTTAATCATGTTTGA
  ATGTTAGGGGTTGGATCCTAGAGTAGATGCCTGAGGCCACATCTGAACAGACCTGTCAGC
  CAGGCCTGCCAGGTCTTCACGTTGAGGATTCAACTGGCCAATCACAGGACAGGTGTCCTG
  GCCTTTCTTCCTGAGGTCTCTAGGGGAGGGGCATGGGTAAGGGTGTTTCCTCAGCACCCT
  CCTGGGGTGGGGATTATGTCTGCTGTCATGTCTGGGTCTTTAGGGTAGGACAGGCTGTGG
  TATGAGAGGCAGGAGTCTCCACAAGGCTTCATGTGGCCCCTTATAGGGCAGGCCCTGCCC
  TCTGGGAAGGTCCCTTCATGCTGGAGGCACACAGCTTTAAGGAAGTAGGTTGAAGTAGGA
  CTCCTTCGTCCTCTCACTGGCTTTGGCTCCCTCAATAAACTGTGTGGGAACCTGAAAAAA
  AAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_025230
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_025230.3, NP_079506.3
• RefSeq Size: 4286 bp
• RefSeq ORF: 1641 bp
• Locus ID: 80344
• UniProt ID: Q8TEB1
• Cytogenetics: 14q12
• Domains: WD40
• Gene Summary: This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2009]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Both variants 1 and 3 encode the same isoform.